1 day ago · The meaning of OPTIMIZE is to make as perfect, effective, or functional as possible. How to use optimize in a sentence. We need to optimize our use of the existing technology. If you optimize the production process you could speed up the assembly line dramatically. The stimulus was viewed with natural pupils to optimize … Find 53 different ways to say OPTIMIZE, along with antonyms, related words, and example sentences at Thesaurus.com. OPTIMIZE definition: to make as effective, perfect, or useful as possible. See examples of optimize used in a sentence. To optimize a plan, system, or machine means to arrange or design it so that it operates as smoothly and efficiently as possible. Optimize means to make the best possible use of something. If you optimize your home storage capacity, you clean and organize your closets and drawers to be able to fit the most in. Definition of optimize verb in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more. Find 822 synonyms for optimize and other similar words that you can use instead based on 4 separate contexts from our thesaurus.